Benzeneboronic acid, pinacol ester
(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
CAS: 24388-23-6
Molecular Formula: C12H17BO2
Benzeneboronic acid, pinacol ester - Names and Identifiers
Benzeneboronic acid, pinacol ester - Physico-chemical Properties
| Molecular Formula | C12H17BO2 |
| Molar Mass | 204.07 |
| Density | 0.99±0.1 g/cm3(Predicted) |
| Melting Point | 27-31°C(lit.) |
| Boling Point | 130°C/20mmHg(lit.) |
| Flash Point | 225°F |
| Vapor Presure | 0.00586mmHg at 25°C |
| Appearance | powder to lump |
| Color | White to Almost white |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.49 |
Benzeneboronic acid, pinacol ester - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29319090 |
| Hazard Note | Irritant |
Benzeneboronic acid, pinacol ester - Introduction
(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl) benzene((4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl) benzene) is an organic compound, its molecular formula is C14H19BO2.
The compound has the following properties:
-Appearance: Colorless solid
-Solubility: Soluble in organic solvents such as chloroform, ether, dichloromethane
-Melting Point: about 80-82 ℃
-Stability: Insoluble in water, but may hydrolyze in a humid environment
The main use of this substance is as a reagent and catalyst in organic synthesis. It is commonly used in platinum-catalyzed Suzuki coupling reactions for the synthesis of different types of organic compounds, such as heterocyclic compounds and drug molecules.
A common method for preparing (4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzene is to react hydrogenated tetramethyldiborane with bromobenzene. The specific reaction conditions can be adjusted according to the experimental requirements.
When using and handling (4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzene, you need to pay attention to the following safety information:
-Wear appropriate protective equipment, such as gloves and glasses, for laboratory operations.
-Avoid direct contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Keep away from combustibles and high-temperature fire sources to avoid contact with fire sources.
-storage should be sealed in a dry, cool place.
The compound has the following properties:
-Appearance: Colorless solid
-Solubility: Soluble in organic solvents such as chloroform, ether, dichloromethane
-Melting Point: about 80-82 ℃
-Stability: Insoluble in water, but may hydrolyze in a humid environment
The main use of this substance is as a reagent and catalyst in organic synthesis. It is commonly used in platinum-catalyzed Suzuki coupling reactions for the synthesis of different types of organic compounds, such as heterocyclic compounds and drug molecules.
A common method for preparing (4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzene is to react hydrogenated tetramethyldiborane with bromobenzene. The specific reaction conditions can be adjusted according to the experimental requirements.
When using and handling (4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzene, you need to pay attention to the following safety information:
-Wear appropriate protective equipment, such as gloves and glasses, for laboratory operations.
-Avoid direct contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Keep away from combustibles and high-temperature fire sources to avoid contact with fire sources.
-storage should be sealed in a dry, cool place.
Last Update：2024-04-09 19:05:48
